Patient Archive

About the resource

Type of resource: ontology-based deep clinical phenotype profiles
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Description

Patient Archive (PA) is a platform developed by the RD-Connect partners at the Garvan Institute of Medical Research, as part of the Monarch Initiative. PA translates deep clinical phenotyping and genome-scale biology to patient-centered human disease pathogenesis. The detailed phenotype profile created in PA, combined with data helps identify the causes of the disease, and make clear diagnosis and prognosis. PA’s innovative features make use of the Human Phenotype Ontology (HPO).

Unlike other existing phenotyping platforms, PA creates a patient clinical phenotype profile by automatic extraction of HPO concepts from free text clinical records or the labels of uploaded images. The HPO terms are then used for patient matchmaking, disorder prediction or gene list generation.

Clinical data exchange is protected with secure access control on an individual or group context, with full integration into the Global Alliance for Genetic Health MatchMaker Exchange. Program. Patient Archive helps to harmonize phenomic information to enable the acceleration of translational and clinical applications.