Leiden Open Variation Database (LOVD)

About the resource

Type of resource: Mutation database
License/availability: Open source
Website: Click here to view website
User documentation: Click here to view documentation
Relevant publication:


LOVD is designed to provide a flexible, freely available tool for gene-centered collection and display of DNA variations. LOVD 3.0 extends this idea to also provide patient-centered data storage and storage of NGS data, even of variants outside of genes. It is becoming the world standard for locus specific databases and there are >80 installations worldwide covering >5,000 genes. To maintain the high quality of the data stored, LOVD connects with various resources, like HGNC, NCBI, EBI and Mutalyzer.